• Mission
  • Contact Us
  • Privacy Policy
  • Subscribe
  • Terms of Service
Conscious Life News
5-day Holosync Challenge
  • Home
  • Conscious Living
    • Activism
    • Animals and Pets
    • Conscious Evolution
    • Conscious Parenting
    • Happiness & Humor
    • Inspirational
    • Manifestation / LOA
    • Meditation
    • Peace & Human Rights
    • Relationships & Sex
    • Thrive
  • Economy
    • Business
    • Education
    • Loans and Frugal Living
    • Investing and Insurance
  • Environ.
    • Climate Change
    • Eco-Friendly
    • Farming & Gardening
    • Environmental Hazards
    • Nature & Wildlife
    • Preparedness
  • Govt.
    • Agencies & Systems
    • The Fed & Banking Cartel
    • Censorship
    • Govt. Corruption
    • Internet Control
    • Military Industrial Complex
    • Policies
    • Politics
    • Govt. Surveillance
    • Whistleblower
  • Health
    • Alternative Health Care
    • Big Pharma, CDC & FDA
    • COVID-19 Vaccine
    • Diet, Weight Loss, Obesity
    • Exercise and Fitness
    • Food, Drink & Nutrition
    • Healing & Natural Remedies
    • Herbs, Seeds & Spices
    • Human Energy Systems
    • Longevity & Life Extension
    • Mind-Body Connection
    • Pet and Animal Health
    • Prevention
    • Skin & Hair Care
  • Horoscopes
  • Media
    • Alternative Media
    • Books
    • Art and Music
    • Corporate Controlled Media
    • Films & TV
    • Internet
    • Social Media
  • Reality’s Edge
    • Afterlife & Past Lives
    • Ascension
    • Astrology & Numerology
    • Channeling & Readings
    • Dreams, ESP & Remote Viewing
    • Dying, NDE, & OBE
    • ETs, UFOs & Crop Circles
    • Mandela Effect
    • Mysteries
    • Predictions & Prophecies
    • Quantum Physics
    • Reality Shifts & Timelines
    • Spirituality and Religion
    • Angels & Spirits
  • Sci-Tech
    • Archaeology
    • Earth & Space
    • Futurism & Inspiring Inventions
    • Medical Advances & Procedures
    • Nature
    • Psychology-Psychiatry
    • Science
    • Technology
No Result
View All Result
  • Home
  • Conscious Living
    • Activism
    • Animals and Pets
    • Conscious Evolution
    • Conscious Parenting
    • Happiness & Humor
    • Inspirational
    • Manifestation / LOA
    • Meditation
    • Peace & Human Rights
    • Relationships & Sex
    • Thrive
  • Economy
    • Business
    • Education
    • Loans and Frugal Living
    • Investing and Insurance
  • Environ.
    • Climate Change
    • Eco-Friendly
    • Farming & Gardening
    • Environmental Hazards
    • Nature & Wildlife
    • Preparedness
  • Govt.
    • Agencies & Systems
    • The Fed & Banking Cartel
    • Censorship
    • Govt. Corruption
    • Internet Control
    • Military Industrial Complex
    • Policies
    • Politics
    • Govt. Surveillance
    • Whistleblower
  • Health
    • Alternative Health Care
    • Big Pharma, CDC & FDA
    • COVID-19 Vaccine
    • Diet, Weight Loss, Obesity
    • Exercise and Fitness
    • Food, Drink & Nutrition
    • Healing & Natural Remedies
    • Herbs, Seeds & Spices
    • Human Energy Systems
    • Longevity & Life Extension
    • Mind-Body Connection
    • Pet and Animal Health
    • Prevention
    • Skin & Hair Care
  • Horoscopes
  • Media
    • Alternative Media
    • Books
    • Art and Music
    • Corporate Controlled Media
    • Films & TV
    • Internet
    • Social Media
  • Reality’s Edge
    • Afterlife & Past Lives
    • Ascension
    • Astrology & Numerology
    • Channeling & Readings
    • Dreams, ESP & Remote Viewing
    • Dying, NDE, & OBE
    • ETs, UFOs & Crop Circles
    • Mandela Effect
    • Mysteries
    • Predictions & Prophecies
    • Quantum Physics
    • Reality Shifts & Timelines
    • Spirituality and Religion
    • Angels & Spirits
  • Sci-Tech
    • Archaeology
    • Earth & Space
    • Futurism & Inspiring Inventions
    • Medical Advances & Procedures
    • Nature
    • Psychology-Psychiatry
    • Science
    • Technology
No Result
View All Result
Conscious Life News
No Result
View All Result
Home Sci-Tech Medical Advances & Procedures

New Discovery Shows Human Cells Can Write RNA Sequences into DNA

by clnAdrian
June 13, 2021
in Medical Advances & Procedures, Sci-Tech, Science
Reading Time: 3 mins read
0 0
A A
0
New Discovery Shows Human Cells Can Write RNA Sequences into DNA
1
SHARES
590
VIEWS
Share on FacebookShare on TwitterShare on WhatsApp
Print Friendly, PDF & Email

Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell. That same class of machines, called polymerases, also build RNA messages, which are like notes copied from the central DNA repository of recipes, so they can be read more efficiently into proteins. But polymerases were thought to only work in one direction DNA into DNA or RNA. This prevents RNA messages from being rewritten back into the master recipe book of genomic DNA. Now, Thomas Jefferson University researchers provide the first evidence that RNA segments can be written back into DNA, which potentially challenges the central dogma in biology and could have wide implications affecting many fields of biology.

“This work opens the door to many other studies that will help us understand the significance of having a mechanism for converting RNA messages into DNA in our own cells,” says Richard Pomerantz, Ph.D., associate professor of biochemistry and molecular biology at Thomas Jefferson University. “The reality that a human polymerase can do this with high efficiency, raises many questions.” For example, this finding suggests that RNA messages can be used as templates for repairing or re-writing genomic DNA.

The work was published June 11th in the journal Science Advances.

Together with first author Gurushankar Chandramouly and other collaborators, Dr. Pomerantz's team started by investigating one very unusual polymerase, called polymerase theta. Of the 14 DNA polymerases in mammalian cells, only three do the bulk of the work of duplicating the entire genome to prepare for cell division. The remaining 11 are mostly involved in detecting and making repairs when there's a break or error in the DNA strands. Polymerase theta repairs DNA, but is very error-prone and makes many errors or mutations. The researchers, therefore, noticed that some of polymerase theta's “bad” qualities were ones it shared with another cellular machine, albeit one more common in viruses—the reverse transcriptase. Like Pol theta, HIV reverse transcriptase acts as a DNA polymerase, but can also bind RNA and read RNA back into a DNA strand.

In a series of elegant experiments, the researchers tested polymerase theta against the reverse transcriptase from HIV, which is one of the best-studied of its kind. They showed that polymerase theta was capable of converting RNA messages into DNA, which it did as well as HIV reverse transcriptase, and that it actually did a better job than when duplicating DNA to DNA. Polymerase theta was more efficient and introduced fewer errors when using an RNA template to write new DNA messages, than when duplicating DNA into DNA, suggesting that this function could be its primary purpose in the cell.

The group collaborated with Dr. Xiaojiang S. Chen's lab at USC and used X-ray crystallography to define the structure and found that this molecule was able to change shape in order to accommodate the more bulky RNA molecule—a feat unique among polymerases.

“Our research suggests that polymerase theta's main function is to act as a reverse transcriptase,” says Dr. Pomerantz. “In healthy cells, the purpose of this molecule may be toward RNA-mediated DNA repair. In unhealthy cells, such as cancer cells, polymerase theta is highly expressed and promotes cancer cell growth and drug resistance. It will be exciting to further understand how polymerase theta's activity on RNA contributes to DNA repair and cancer cell proliferation.”

More information: Polθ reverse transcribes RNA and promotes RNA-templated DNA repair, Science Advances (2021). DOI: 10.1126/sciadv.abf1771

Journal information: Science Advances

Provided by Thomas Jefferson University

Source: phys.org

Tags: DNA engineeringfeaturedhuman cellsRNA messagesRNA sequencesRNA sequences into DNAsequence of RNAsingle-cell RNA-sequencingThomas Jefferson UniversityThomas Jefferson University researchers
ShareTweetSend
Previous Post

The Perfect Paradox: Letting Go Is The Key That Opens The Door to Fulfillment

Next Post

MCAT Test to Apply for Medical School

Related Posts

University Study Determines that Fire Did NOT Bring Down World Trade Center Building 7 on 9/11
Sci-Tech

University Study Determines that Fire Did NOT Bring Down World Trade Center Building 7 on 9/11

September 11, 2024
The End of Humanity – As Planned By The Global Leaders
Activism

The End of Humanity – As Planned By The Global Leaders

April 26, 2024
Google Gemini AI Is Anti-White – and So Is Google Search
Technology

Google Gemini AI Is Anti-White – and So Is Google Search

February 26, 2024
Through the Quantum Looking Glass: How Consciousness Creates Our Reality
Quantum Physics

Through the Quantum Looking Glass: How Consciousness Creates Our Reality

September 14, 2023
How Scientists Proved the Universe is NOT REAL: Nobel Prize Winning Proof EXPLAINED
Quantum Physics

How Scientists Proved the Universe is NOT REAL: Nobel Prize Winning Proof EXPLAINED

June 4, 2023
Reality Is An Illusion – Scientific Proof PLUS 77 Additional Reasons To Believe It’s True
Conscious Living

Nobel Prize in Physics Awarded for Proving the Universe Is Not Real | Where Quantum Physics Meets Vedanta

April 25, 2023
Next Post

MCAT Test to Apply for Medical School

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Conscious Life News

The mission of Conscious Life News is to be a global leader in the consciousness-raising of the planet.

Follow Us

Browse by Category

  • Activism
  • Afterlife & Past Lives
  • Agencies & Systems
  • Alternative Health Care
  • Alternative Media
  • Angels & Spirits
  • Animals and Pets
  • Archaeology
  • Art and Music
  • Artificial Intelligence
  • Ascension
  • Astrology & Numerology
  • Astrology Overview
  • Big Pharma, CDC, FDA & NIH
  • Books
  • Business
  • Careers
  • Censorship
  • Channeling & Readings
  • Climate Change
  • Conscious Evolution
  • Conscious Living
  • Conscious Parenting
  • Corporate Controlled Media
  • COVID-19 Vaccine
  • Daily
  • Diet, Weight Loss, Obesity
  • Dreams, ESP & Remote Viewing
  • Dying, NDE, & OBE
  • Earth & Space
  • Eco-Friendly
  • Economy
  • Education
  • Environment
  • Environmental Hazards
  • ETs, UFOs & Crop Circles
  • Exercise and Fitness
  • Farming & Gardening
  • Featured
  • Federal Law
  • Films & TV
  • Food, Drink & Nutrition
  • Futurism & Inspiring Inventions
  • Government
  • Govt Censorship
  • Govt. Corruption
  • Govt. Surveillance
  • Happiness & Humor
  • Healing & Natural Remedies
  • Health
  • Herbs, Seeds & Spices
  • Home Maintenance, Repairs & Improvement
  • Horoscopes
  • Human Energy Systems
  • Inspirational
  • Internet
  • Internet Control
  • Investing and Insurance
  • Laws and Lawyers
  • Lifestyle and Fashion
  • Loans and Frugal Living
  • Longevity & Life Extension
  • Mandela Effect
  • Manifestation / LOA
  • Maya / Matrix / Virtual Reality
  • Media & Arts
  • Medical Advances & Procedures
  • Meditation
  • Military Industrial Complex
  • Mind-Body Connection
  • Monthly
  • Mysteries
  • Nature
  • Nature & Wildlife
  • News Flash
  • Peace & Human Rights
  • Pet and Animal Health
  • Policies
  • Politics
  • Predictions & Prophecies
  • Preparedness
  • Prevention
  • Psychology-Psychiatry
  • Quantum Physics
  • Reality Shifts & Timelines
  • Reality's Edge
  • Relationships & Sex
  • Sci-Tech
  • Science
  • Skin & Hair Care
  • Social Media
  • Spirituality and Religion
  • Stuff
  • Technology
  • The Fed & Banking Cartel
  • Thrive
  • Uncategorized
  • Weekly
  • Whistleblower
  • World

Recent News

Scorpio Full Moon Deep Dive Video + Zodiac Forecasts All Signs

Scorpio Full Moon Deep Dive Video + Zodiac Forecasts All Signs

May 11, 2025
Weekly Astrology Video WC 12th May 2025 + All Signs…

Weekly Astrology Video WC 12th May 2025 + All Signs…

May 11, 2025

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist

No Result
View All Result

© 2023 ConsciousLifeNews.com - Premium WordPress news & magazine theme by Jegtheme.

This website uses cookies. By continuing to use this website you are giving consent to cookies being used. Visit our Privacy and Cookie Policy.