STORY AT-A-GLANCE
- According to interim estimates, the overall adjusted effectiveness of the 2018-19 flu vaccine against all influenza virus infection associated with acute respiratory illness (ARI) needing medical attention was 47 percent
- Among adults over 50, the vaccine had a mere 24 percent effectiveness against all influenza types, and an abysmal 8 percent against influenza A(H1N1)pdm09 infection, which was by far the most common type
- Of all who came down with ARI, only 14 percent actually had influenza. In the vast majority of cases — 86 percent — their respiratory illness was caused by something other than an influenza virus
- There are more than 200 viruses that cause influenza-like illness with identical symptoms as influenza, such as fever, headache, aches, pains, cough and runny nose. The flu vaccine does not prevent these illnesses
- Research published last year found people who had received a flu shot and contracted influenza shed a greater amount of influenza viruses through their breath than unvaccinated people
Written by Dr. Joseph Mercola
According to interim estimates1 released by the U.S. Centers for Disease Control and Prevention (CDC) on February 15, 2019 — which uses data from 3,254 adults and children enrolled in the U.S. Influenza Vaccine Effectiveness Network between November 23, 2018, and February 2, 2019 — the overall adjusted effectiveness of the 2018-19 flu vaccine against all influenza virus infection associated with acute respiratory illness (ARI) needing medical attention was 47 percent.
While the media has played this up as “good news,”2 and the CDC calls the results “encouraging,”3 the fact of the matter is the vaccine failed to offer any protection more than half of the time, and for adults over 50, it's more or less useless.
This Year's Flu Vaccine Is an Abysmal Failure for Those Over 50
Among children aged 6 months to 17 years, the 2018–19 seasonal flu vaccine had an average effectiveness of 61 percent.4 However, among adults over 50, which is the most vulnerable group, the vaccine had a mere 24 percent effectiveness against all influenza types, and an abysmal 8 percent against influenza A(H1N1)pdm09 infection, which was by far the most common type.
According to the CDC, the A(H1N1)pdm09 virus was responsible for 74 percent of all influenza A infections for which subtype information was available. What's more, the CDC notes that,5 “Among the 3,254 children and adults with ARI … a total of 465 (14 percent) tested positive for influenza virus by real time RT-PCR …”
In other words, of all the people who came down with acute respiratory illness, only 14 percent actually had confirmed influenza. In the vast majority of cases — 86 percent — their respiratory illness was associated with a viral or bacterial infection caused by something other than a type A or B influenza virus.
This is important to remember, as people have a tendency to jump to the conclusion that when they have influenza-like illness (ILI) symptoms they have influenza when, in fact, chances are the majority of the time they don't.
The influenza vaccine contains only three or four type A or B vaccine strain influenza viruses. Even if those vaccine strain viruses are a perfect match for influenza viruses that are circulating in a given flu season, the vaccine does not prevent the majority of other respiratory infections that are experienced by people. As noted by the Cochrane Collaboration:6
“Over 200 viruses cause ILI (influenza-like illness), which produces the same symptoms (fever, headache, aches, pains, cough and runny nose) as influenza. Without laboratory tests, doctors cannot distinguish between ILI and influenza because both last for days and rarely cause serious illness or death.”
The 2017/2018 seasonal influenza vaccine's adjusted overall effectiveness for the U.S. was just 36 percent against influenza A and influenza B virus infection,7,8 and between 2005 and 2015, the flu vaccine's adjusted overall effectiveness was less than 50 percent more than half the time — with a low of only 10 percent in the 2004-05 season.9,10
It's difficult to find another example of where a commercial product can fail to work more than half the time and still be recommended and even mandated for children and adults.
Obesity Is a Major Cause of Influenza Outbreaks and Vulnerability
In related news, research suggests widespread obesity may be a significant contributor to influenza outbreaks and general vulnerability, as obesity makes you shed and transmit virus for a longer period of time, thereby increasing the opportunity for spreading infections to others. According to this study,11 published in the September, 2018 issue of The Journal of Infectious Diseases:
“[O]besity increases the risk of severe complications and death from influenza virus infection, especially in elderly individuals … Symptomatic obese adults were shown to shed influenza A virus 42 percent longer than nonobese adults … no association was observed with influenza B virus shedding duration. Even among paucisymptomatic and asymptomatic adults, obesity increased the influenza A shedding duration by 104 percent.”
Aubree Gordon, Ph.D., senior author from the University of Michigan School of Public Health, told reporters,12 “This is the first real evidence that obesity might impact more than just disease severity. It might directly impact transmission as well.”
Additional research is underway to analyze whether influenza virus shed over longer periods is still equally infectious. The answer here, of course, would be to normalize your weight and strengthen your immune function. You can find more information about these strategies in the hyperlinked articles.
Flu Vaccine Still Allows Transmission of Disease
Obesity isn't the only thing that might contribute to influenza outbreaks. A study13 published in the journal PNAS January 18, 2018, found infectious influenza viruses in the exhaled breath of people who had gotten seasonal flu shots and contracted influenza. Those vaccinated two seasons in a row had an even greater viral load of shedding influenza A viruses. According to the authors:
“Self-reported vaccination for the current season was associated with a trend toward higher viral shedding in fine-aerosol samples; vaccination with both the current and previous year's seasonal vaccines, however, was significantly associated with greater fine-aerosol shedding in unadjusted and adjusted models.
In adjusted models, we observed 6.3 times more aerosol shedding among cases with vaccination in the current and previous season compared with having no vaccination in those two seasons … The association of vaccination and shedding was significant for influenza A but not for influenza B infections …
Finding infectious virus in 39 percent of fine-aerosol samples collected during 30 minutes of normal tidal breathing in a large community-based study of confirmed influenza infection clearly establishes that a significant fraction of influenza cases routinely shed infectious virus … into aerosol particles small enough to remain suspended in air and present a risk for airborne transmission …
The association of current and prior year vaccination with increased shedding of influenza A might lead one to speculate that certain types of prior immunity promote lung inflammation, airway closure and aerosol generation …
If confirmed, this observation, together with recent literature suggesting reduced protection with annual vaccination, would have implications for influenza vaccination recommendations and policies.”
Mounting Body of Research Questions Validity of Annual Flu Vaccination as a Public Health Measure
On the whole, there's really very little evidence to suggest annual flu vaccinations are a good way to combat influenza and save lives. On the contrary, the medical literature is burgeoning with studies questioning the validity of this public health measure. For example, studies have shown that:
| With each successive annual flu vaccination, the theoretical protection from the vaccine can diminish14 — A 2012 Chinese study15 found a child's chances of contracting a respiratory infection after getting the seasonal flu shot rose more than fourfold, and research published in 2014 concluded that resistance to influenza-related illness in persons over age 9 years in the U.S. was greatest among those who had NOT received a flu shot in the previous five years.16 More recent research suggests the reason seasonal flu shots become less protective with each dose has to do with “original antigenic sin.” Here, they found that influenza vaccine failed to elicit a strong immune response in most participants,17 which was explained as follows:18
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71 people have to be vaccinated for a single case of influenza to be avoided, and vaccination has “little or no appreciable effect on hospitalizations or number of working days lost” — In its 2014 meta-analysis19 of the available research on inactivated influenza vaccines, the Cochrane Collaboration reviewed evidence related to influenza and influenza-like illness (ILI) that people experience during flu seasons, concluding that:
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| The flu vaccine can increase your risk of contracting other, more serious influenza infections — Canadian researchers found that people who had received the seasonal flu vaccine in 2008, on average, had twice the risk of getting sick with the pandemic H1N1 “swine flu” in 2009 compared to those who did not receive a flu shot the previous year.20 These findings were replicated in a 2014 ferret study.21 Similarly, a 2009 U.S. study compared health outcomes for children between age 6 months and 18 years who did and did not get annual flu shots and found that children who received influenza vaccinations had a three times' higher risk of influenza-related hospitalization, with asthmatic children at greatest risk.22 The concept of heterologous immunity may account for these findings. Heterologous immunity refers to the concept that your immune system is directional, and that once you've encountered a pathogen, your body is better equipped to fight pathogens that are similar. However, in the case of influenza vaccines, this directionality appears to work against you. By learning to fend off certain influenza virus strains contained in the vaccine, your immune system becomes less able to fend off other influenza strains and disease-causing pathogens. As noted in a 2014 paper on heterologous immunity:23
In other words, while influenza vaccine may offer some level of protection against the three or four viral influenza strains included in the vaccine, depending on whether the vaccine used is trivalent or quadrivalent, it may simultaneously diminish your ability to ward off infection by other influenza strains and types of viral or bacterial infections. Heterologous immunity is also addressed in a 2013 paper,24 which notes that “vaccines modulate general resistance,” and “have nonspecific effects on the ability of the immune system to handle other pathogens.” Researchers stated that:
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| Flu vaccine doesn't work well in statin users — Statin drugs may interfere with your immune system's ability to respond to the influenza vaccine.25,26 After vaccination, antibody concentrations were 38 percent to 67 percent lower in statin users over the age of 65, compared to nonstatin users of the same age.27 Antibody concentrations were also reduced in younger people who took statins. |
| Flu vaccine does not prevent most types of influenza — Independent scientific reviews have also concluded that flu shots have only a “modest effect in reducing influenza symptoms and working days lost,” and have no effect on complications of influenza.28,29 Moreover, the influenza vaccine fails to prevent influenza-like illness associated with other types of viruses responsible for about 80 percent of all respiratory or gastrointestinal infections during any given flu season.30,31,32,33,34 |
| Vaccination does not lower mortality in the elderly — Research35 published in 2006 analyzed influenza-related mortality among the elderly population in Italy associated with increased vaccination coverage between 1970 and 2001. Researchers found that after the 1980s, there was no corresponding decline in excess deaths, despite rising vaccine uptake. According to the authors, “our study challenges current strategies to best protect the elderly against mortality, warranting the need for better controlled trials with alternative vaccination strategies.” Another 2006 study36 showed that, even though seniors vaccinated against influenza had a reduced risk of dying during flu season compared to unvaccinated seniors, those who were vaccinated were also even more unlikely to die before the flu season ever started. This finding has since been attributed to a “healthy user effect,” which suggests that older people who get vaccinated against influenza are already healthier and, therefore, less likely to die anyway, whereas those who do not get the shot have suffered a decline in health in recent months. |
| “New and improved” flu shot also fails to protect seniors — The Flucelvax vaccine introduced during the 2017-2018 flu season is grown in dog kidney cells rather than chicken eggs. Touted as a new-and-improved flu shot that would protect more people, Food and Drug Administration research found no significant difference between it and the conventional flu shot in protecting seniors. While flu vaccines overall had a 24 percent effectiveness in preventing flu-related hospitalizations in people aged 65 and older, the Flucelvax vaccine had an effectiveness rate of only 26.5 percent in that population.37 |
Flu vaccine does not lessen influenza severity — While health officials claim getting a flu shot will lessen your symptoms should you contract influenza, a 2017 study38 by French researchers assessing the veracity of that claim found it to be false. Looking at data from vaccinated and unvaccinated elderly patients diagnosed with influenza, all they found was a reduction in initial headache complaints among those who had been vaccinated. According to the authors:
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| Flu vaccine is associated with serious disability — Permanent disability such as paralysis from Guillain-Barre Syndrome (GBS) is a risk you need to take into account each time you get a flu shot. As early as 2003, the CDC recognized the flu vaccine causes an excess of 1.7 cases of GBS per 1 million people vaccinated.39 Data from the U.S. Department of Health and Human Services shows GBS is the top injury for which people are receiving financial compensation through the federal vaccine injury compensation program (VICP), and the flu vaccine is now the most common vaccine cited by adults seeking a vaccine injury compensation award.40 Shoulder damage is another risk, caused by improper injection technique.41,42,43 Shoulder injury related to vaccine administration (SIRVA) includes chronic pain, limited range of motion, nerve damage, frozen shoulder and rotator cuff tears, and is typically the result of the injection being administered too high on the arm. This risk is particularly high when people get vaccinated outside of a doctor's office or other clinical setting. Many people getting flu shots in a public setting like a grocery store or pharmacy simply roll up their sleeves or pull down the top of their shirt, exposing only the upper part of their deltoid, thereby increasing the risk of getting the injection in the joint space rather than the muscle. GBS and SIRVA were both added to the Vaccine Injury Table of the VICP in 2017.44,45 By adding those vaccine complications to the table, vaccine-related GBS and SIRVA cases brought before the “Vaccine Court” in the U.S. Court of Federal Claims in Washington, D.C., will be more likely to receive federal vaccine injury compensation. In this lecture, immunologist Tetyana Obukhanych, Ph.D., author of “Vaccine Illusion: How Vaccination Compromises Our Natural Immunity and What We Can Do to Regain Our Health,” explains how vaccines damage your immune function, which can result in any number of adverse health effects. |
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