Scientists Discover Enzyme With The Potential To Treat Obesity and Type 2 Diabetes

Written by on February 1, 2016 in Diet, Weight Loss, Obesity, Health with 7 Comments


By Number23 | We Are Anonymous

Scientist have recently discovered an enzyme that could potentially lead to an effective treatment for obesity and type 2 diabetes.

This previously unknown enzyme, a protein known as “glycerol-3-phosphate phosphatase”, or G3PP,“converts a harmful byproduct of glucose into a non-toxic compound known as glycerol.”

Typically, when too much sugar is consumed, the body creates and organ-damaging chemical called glycerol-3-phosphate, which affects the inner workings of cells and alters the body’s metabolism. As a result, glucose levels are raised, which threatens the insulin-producing pancreas, liver, and other organs.

Hormone G3PP, which has been outlined in the Proceedings of the National Academy of Sciences,works by breaking down that chemical and flushing it out of the cells, which in turn reins in glucose, protecting the organs from harm.

It is extremely rare since the 1960s that a novel enzyme is discovered at the heart of metabolism of nutrients in all mammalian tissues, and likely this enzyme will be incorporated in biochemistry textbook,” said Dr. Marc Prentki, one of the researchers leading the study at the University of Montreal Hospital Research Center.

Before this discovery, G3PP had been identified in bacteria, algae and yeast, but was not thought to exist in humans. However, according to the study, the enzyme can help metabolise nutrients in the cells of all mammals.

We found that G3PP is able to break down a great proportion of this excess glycerol phosphate into glycerol and divert it outside the cell, thus protecting the beta cells of the pancreas and various organs from the toxic effects,said co-author Marc Prentki.

Although this is largely theoretical science—additional animal and human trials are needed to see how the process works when put into practice—the researchers believe that this discovery has the potential to lead to drug therapy for obesity and diabetes.

“Once these compounds are fully characterised, they will be developed as potential drugs,” said Dr Madiraju, of the University of Montreal Hospital Research Centre.

This Article (Scientists Discover Enzyme With The Potential To Treat Obesity and Type 2 Diabetes) is free and open source. You have permission to republish this article under a Creative Commons license with attribution to the author and

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7 Reader Comments

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  1.' Baba Loblaw says:

    Unfortunately Big Pharma Will manipulate this enzyme too and it will cause more side effects than benefits.

  2.' Rex Berrien says:

    Magic pill research never works, been hearing this kind of stuff for years. It won’t happen, Doctors and Big Pharma making too much money from Obesity and Diabetes II.

  3.' Dana Browning says:

    Eat real food. This makes me more disappointed in the site.

  4.' Muriel Muller says:

    Eat healthy food in reasonable quantity and you will never need any of these!

  5.' Ajay Pakhrin says:

    Yes I think so it’s true .

  6.' Patricia Anne Morgan says:

    Or…….people could start taking care of themselves, heaven forbid.

  7.' Sheron McRoberts says:

    They have had a cure for obesity for years but if they really release it and save lives then they would stop all these greedy bastards from making billions off of people’s misery ! Just think of all the doctors and diet company’s and pharmaceutical company’s out of business. No more heart issues diabetics strokes all the real money makers for the greedy monsters in our society!

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